For example, swine are used for cardiovascular research (particularly atherosclerosis), in studies of digestive physiology, as surgical models, and for xenotransplantation. All experimental programmes supported by MRC must avoid using animals wherever possible.The researcher must give sound scientific reasons for their use,and explain why there are no realistic alternatives. From my experience the most common strain of mice in research is C57BL/6 generally called Black6. Research with genetically modified mice and rats has led to significant new treatments, cures and therapies and continues to revolutionize science and medicine. According to the Foundation for Biomedical Research, approximately 95% of all lab animals used for biomedical research are rats and mice. An indeed staggering number but have you ever wondered why? Although mice are widely used in research, questions remain about their reliability as a model for human diseases. The phenotype (main outward appearance) of the mouse is a lack … A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. They have a black coat color. Well, we certainly did, so we decided to look for the answer. Mice and Medicine.

There are mice and rats used in research for cancer, genetics, immunology, virology, the behavioral sciences, aging, HIV/AIDS, Alzheimer’s, alcoholism, diabetes, obesity, radiation effects, drug addiction, new drug testing and more. BALB-C is another very common strain used in research and they are albino (white coat). For example, many drugs work well in preclinical trials in mice but turn out to be ineffective when used in clinical trials on humans. Sheep are used for studies of neonatal development, human vaccine improvement, asthma pathogenesis and treatment, drug delivery, circadian rhythms, and surgical techniques. Mice and Rats in Research To the best of our knowledge, every field of research includes the use of mice and rats in experimentation.

Cancer Rodents have contributed to cancer research for more than a century [2] . The MRC only supports scientific studies which are well designed and likely to provide new information on important questions relevant to human health.