The % yield was calculated and the purity of the aspirin was tested with ferric chloride. Many different laboratory techniques are used in the synthesis of Aspirin. Aspirin has been used as a medicine by the ancient Greeks and the pharaohs of Egypt. aspirin to diminish inflammation is due to its inhibition of the synthesis of prostaglandins. In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride. Abstract: The purpose of this experiment was to synthesize aspirin from salicylic acid and acetic anhydride. The Synthesis and Analysis of Aspirin Mariam El-Magbri Department of Chemistry, American University, Washington, D.C. 20016 Date of Publication: February 26, 2014 ABSTRACT: Acetylsalicylic acid commonly known as aspirin is the most widely used drug in … Put the plate onto its hottest setting, once the water is boiling reduce the setting & using a thermometer maintain a temperature of around 100 0 Measure out 2g of Salicylic Acid on a weighing boat and place into a 50ml Conical flask. It is effective in reducing pain (it is an analgesic), reducing inflammation (anti-inflammatory), reducing fever (antipyretic), and thinning blood (anti-coagulant). Those two chemicals are mixed together along with sulfuric acid to form a crude solid. The mechanism for this synthesis provides examples of three major classes of chemical reactions: hydrolysis, condensation, and proton transfer. To do this, place an arbitrary amount of the substance to be weighed greater than the desired amount on the Fischer balance and press the tare bar to … It is Synthesis of Aspirin Lab Report 2989 Words 12 Pages Abstract: The goal of this experiment was to synthesize aspirin. Aspirin is synthesized from salicylic acid and acetic anhydride. Aspirin alters the oxygenase activity of prostaglandin synthetase by moving the acetyl group to a terminal amine group4. An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples.

The % yield of the aspirin was 132%. It is the two-step synthesis of aspirin starting from oil of wintergreen. Synthesis of Aspirin In the fume hood, place some water in a 600ml beaker and place this onto the hot plate. Though aspirin has numerous benefits, there are several adverse affects as well. ABSTRACT: The purpose of this experiment was to find out how a reaction undergoes for a globally known painkiller called aspirin, and to become familiar with achieving successful yields.

The first of these that is used is the procedure of weighing by difference.