They should be good and famous enough to raise funding for the center/institute. There are a number of websites such as Science Exchange or Assay Depot that outsource lab tasks. Getting ethical clearance (alone) from any independent institute is a good option to ponder. Where appropriate, the VPRED will work with the provost and deans to create a funding plan as long as the center / institute activities meet university goals and objectives. 0) You need to rent/buy a place with several offices and equipment. Conversely, centers and institutes may form and dissolve, recombine and fracture as scholarly problems and issues arise and fade. 1) You need to have productive and creative researchers. However, it depends on the type of research and the Institute's ethical team. The rise of low-cost non-profit open access publishing models is beginning to enable research findings to be shared and further reduce the reliance on the university model of research… As an independent researcher without a doctorate this becomes more difficult but not impossible.

I’d recommend only posting availability for tasks you can perform at no cost, as it’s unlikely you can compete with the university vendors on material cost. Research center mat consist of a handful of researchers focusing on a particular topic whereas Research institute should be much larger.