Therefore, a 10-percent fall in drug prices is likely to cause a 5- to 6-percent decline in both cancer regimens and research articles. The elasticity of journal citations is 0.60. A 10-percent fall in drug prices is likely to cause a 5- to 6-percent decline in both cancer regimens and research articles. Reuters reports that drug makers are raising prices on 250 drugs in 2019, and this has many patients and doctors very concerned. In 2014, the price of one kind of insulin increased by nearly 50 percent, even though it had already been on the market for more than a decade. Evidence We reviewed the peer-reviewed medical and health policy literature from January 2005 to July 2016 for articles addressing the sources of drug prices in the United States, the justifications and consequences of high prices, and possible solutions. OBJECTIVES: To review the origins and effects of high drug prices in the US market and to consider policy options that could contain the cost of prescription drugs. Turing raised the price of the antiparasitic drug Daraprim by 5,500%, from $13.50 to $750 a pill, and Valeant raised the prices of Nitropress and Isuprel—two heart medications—by 525% and 212%, respectively.